Medical Care

Mazzoni Center Family and Community Medicine, 809 Locust StreetMazzoni Center Family and Community Medicine at 809 Locust Street offers compassionate, comprehensive primary health care services focusing on the needs of lesbian, gay, bisexual, and transgender individuals.  With our own caring, professional staff, and through our partnership with Thomas Jefferson University’s Department of Family and Community Medicine, we are able to meet the growing health care demands of Philadelphia’s LGBT communities.


Web-based Patient Portal

Mazzoni Center Family and Community Medicine now has a Patient Web Portal, which means easier access and greater convenience for our patients. 

Through the new system patients can create an online account that lets them request appointments, referrals, and prescriptions, and access test results and medical records 24 hours a day via a secure email connection.

Operating hours for the health center (effective 10/1/15):

Monday: 8 a.m. to 7 p.m.

Tuesday: 9 a.m. to 7 p.m.

Wednesday: 9 a.m. to 5 p.m., with drop-in hours for youth aged 14-24 every Wednesday 5 to 7 p.m.

Thursday: 9 a.m. to 5 p.m.

Friday: 8 a.m. to 5 p.m.

Closed from 12 to 1 p.m. daily for lunch.

To make an appointment at our offices at 809 Locust Street, visit our web-based patient portal anytime.  You can also call the health center at 215-563-0658.  Our fax number is 215-923-0365.

We thank you for your patience, and look forward to serving you!

Current patients can continue to access their records and communicate with our staff via the patient portal

Payment & Insurance

Mazzoni Center currently accepts most major insurers: click here to view the full list. We also accept PA Medicaid and most PA Medicaid HMOs along with Medicare Part B. We DO NOT accept Health Partners, Qual Care, any OUT of state Medicaid, and Military/ Armed Forces insurance plans such as Tricare and Champus. For our non-insured clients we offer low cost copays on a sliding-scale, based on annual income and number of dependents. Please contact our office at (215)563-0658 for more information.

All records are kept confidential.


Medical Staff

View a list of our doctors and clinicians.

Program Services

We offer comprehensive primary health care in an environment conducive to the discussion of LGBTQ health issues. These services include routine health care, preventive health services, gynecology, sexual health services and chronic disease management. As a family medicine practice, we see children and adults of all ages, and especially welcome families. When appropriate, we can refer patients to other Mazzoni Center resources such as mental health programs, smoking cessation classes, and complementary therapies.

Mazzoni Center has partnered with the Family Planning Council to offer reproductive health and family planning services. These services include routine GYN care, contraceptive management, and sexually transmitted infection screening and treatment.

For HIV infected individuals we offer both primary and specialized HIV care. Our clinicians are certified by the American Academy of HIV Medicine and have special interest in the treatment of HIV. Services include routine physicals, medication management, prophylactic treatments, nutritional counseling, treatment adherence counseling, and direct referrals to other Mazzoni Center supportive services as needed. HIV care is provided during all of our patient care hours and does not require a special appointment.

Mazzoni Center has served the LGBT community’s health and wellness needs since 1979.  Serving trans* and gender expansive minors has been woven into the fabric of Mazzoni services for many years, and the challenges our youth face fuels the P.A.C.T.S. team to create inventive, holistic and comprehensive supports.  We recognize that trans* youth and their families have specific needs and questions, and we have developed a comprehensive approach to addressing them. 

Mazzoni Center has contracted with several other providers in Philadelphia to provide various specialty services at the Center. In addition to our family medicine, transgender, HIV/AIDS, and family planning services, we can also help patients in the following areas: Hepatitis Vaccination, Massage Therapy, and Nutritional Counseling.

     Syphilis is a disease transmitted through physical contact from person to person through oral, anal, and vaginal sex. While syphilis is easy to get, it is even easier to treat and cure with antibiotics.  Mazzoni Center offers FREE syphilis screening at our Health Center, Washington West Project, and on our Mobile Testing Unit. 

Regardless of gender identity or gender expression, Mazzoni Center provides compassionate and non-judgmental medical care to Philadelphia’s wonderfully diverse transgender community. We are especially proud of our ability to provide this care and continually seek feedback from the community.

Walgreens Pharmacy at Mazzoni Center is a full-service pharmacy, with a special expertise in HIV/AIDS. They have knowledgeable pharmacists who understand your needs, and are ready to become a critical partner in your healthcare team. They are uniquely trained in the latest HIV/AIDS therapies, and are available for one-on-one medication consultations.

In recent months we've expanded and enhanced our services for women at Mazzoni Center Family & Community Medicine (809 Locust Street).  

Wednesdays from 5 to 7 pm Mazzoni Center offers youth drop-in hours at our Family and Community Medicine practice at 809 Locust Street.